# State Street(R) SPDR(R) S&P(R) Biotech ETF

State Street(R) SPDR(R) S&P(R) Biotech ETF is a ETF series of SPDR SERIES TRUST (series S000010018). Net assets $7.4B as of 2026-03-31. Index fund.

## Profile

- Series ID: S000010018
- Registrant: SPDR SERIES TRUST
- LEI: 549300Y3ODFMPD5XXL58
- Net assets: $7.4B
- Total assets: $8.0B
- As of: 2026-03-31
- Type: ETF, Index

## Advisers

- [SSGA Funds Management, Inc. (Advisor)](https://search.stillhousedata.com/firm/111242)

## Top holdings (158 reported)

_Showing 15 of 158 holdings by value._

| Holding | Ticker | Value | % of fund |
| --- | --- | --- | --- |
| [State Street Global Advisors](https://search.stillhousedata.com/security/857492706) | — | $595.5M | 800.95% |
| [Apellis Pharmaceuticals Inc](https://search.stillhousedata.com/security/03753U106) | — | $136.4M | 183.47% |
| Alkermes PLC | — | $107.9M | 145.10% |
| [Madrigal Pharmaceuticals Inc](https://search.stillhousedata.com/security/558868105) | — | $102.8M | 138.29% |
| [TG Therapeutics Inc](https://search.stillhousedata.com/security/88322Q108) | — | $100.3M | 134.96% |
| [Insmed Inc](https://search.stillhousedata.com/security/457669307) | — | $99.4M | 133.69% |
| [Scholar Rock Holding Corp](https://search.stillhousedata.com/security/80706P103) | — | $96.5M | 129.73% |
| [Apogee Therapeutics Inc](https://search.stillhousedata.com/security/03770N101) | — | $95.5M | 128.43% |
| [Protagonist Therapeutics Inc](https://search.stillhousedata.com/security/74366E102) | — | $92.5M | 124.49% |
| [Summit Therapeutics Inc](https://search.stillhousedata.com/security/86627T108) | — | $92.3M | 124.11% |
| [United Therapeutics Corp](https://search.stillhousedata.com/security/91307C102) | — | $92.2M | 124.05% |
| [Praxis Precision Medicines Inc](https://search.stillhousedata.com/security/74006W207) | — | $91.9M | 123.62% |
| [Arrowhead Pharmaceuticals Inc](https://search.stillhousedata.com/security/04280A100) | — | $91.4M | 122.98% |
| [Cogent Biosciences Inc](https://search.stillhousedata.com/security/19240Q201) | — | $90.4M | 121.57% |
| [Bridgebio Pharma Inc](https://search.stillhousedata.com/security/10806X102) | — | $88.1M | 118.55% |

## Net asset history

| Report date | Net assets |
| --- | --- |
| 2026-03-31 | $7.4B |
| 2025-12-31 | $7.8B |
| 2025-09-30 | $5.7B |
| 2025-06-30 | $4.8B |
| 2025-03-31 | $5.1B |
| 2024-12-31 | $6.4B |
| 2024-09-30 | $7.7B |
| 2024-06-30 | $7.1B |

## More

- [Registrant: SPDR SERIES TRUST](https://search.stillhousedata.com/registrant/1064642)
- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/fund/S000010018.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.