# First Trust NYSE Arca Biotechnology Index Fund

First Trust NYSE Arca Biotechnology Index Fund is a ETF series of First Trust Exchange-Traded Fund (series S000012478). Net assets $2.3B as of 2026-03-31. Index fund.

## Profile

- Series ID: S000012478
- Registrant: First Trust Exchange-Traded Fund
- LEI: 5493003ZQM0TVLDIBC50
- Net assets: $2.3B
- Total assets: $2.3B
- As of: 2026-03-31
- Type: ETF, Index

## Advisers

- [First Trust Advisors L.P. (Advisor)](https://search.stillhousedata.com/firm/107027)

## Top holdings (32 reported)

_Showing 15 of 32 holdings by value._

| Holding | Ticker | Value | % of fund |
| --- | --- | --- | --- |
| [Moderna Inc](https://search.stillhousedata.com/security/60770K107) | — | $119.4M | 526.15% |
| [United Therapeutics Corporation](https://search.stillhousedata.com/security/91307C102) | — | $98.9M | 435.81% |
| Alkermes PLC | — | $96.1M | 423.52% |
| [Gilead Sciences Inc.](https://search.stillhousedata.com/security/375558103) | — | $92.8M | 408.86% |
| [Axsome Therapeutics Inc.](https://search.stillhousedata.com/security/05464T104) | — | $88.2M | 388.55% |
| [Amgen Inc.](https://search.stillhousedata.com/security/031162100) | — | $87.0M | 383.26% |
| [Corcept Therapeutics Inc.](https://search.stillhousedata.com/security/218352102) | — | $86.7M | 381.87% |
| [Krystal Biotech Inc](https://search.stillhousedata.com/security/501147102) | — | $79.7M | 351.04% |
| [Biogen Inc](https://search.stillhousedata.com/security/09062X103) | — | $78.8M | 347.13% |
| [Exelixis, Inc.](https://search.stillhousedata.com/security/30161Q104) | — | $78.5M | 345.98% |
| [Neurocrine Biosciences Inc](https://search.stillhousedata.com/security/64125C109) | — | $78.2M | 344.66% |
| [Regeneron Pharmaceuticals, Inc.](https://search.stillhousedata.com/security/75886F107) | — | $78.2M | 344.59% |
| [Vertex Pharmaceuticals Incorporated](https://search.stillhousedata.com/security/92532F100) | — | $77.6M | 341.93% |
| [Biomarin Pharmaceutical Inc.](https://search.stillhousedata.com/security/09061G101) | — | $77.3M | 340.41% |
| [Argenx SE](https://search.stillhousedata.com/security/04016X101) | — | $74.7M | 329.15% |

## Net asset history

| Report date | Net assets |
| --- | --- |
| 2026-03-31 | $2.3B |
| 2025-12-31 | $1.3B |
| 2025-09-30 | $1.1B |
| 2025-06-30 | $1.0B |
| 2025-03-31 | $1.1B |
| 2024-12-31 | $1.1B |
| 2024-09-30 | $1.2B |
| 2024-06-30 | $1.1B |

## More

- [Registrant: First Trust Exchange-Traded Fund](https://search.stillhousedata.com/registrant/1329377)
- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/fund/S000012478.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.