# AMYLYX PHARMACEUTICALS INC COM

AMYLYX PHARMACEUTICALS INC COM is a security (CUSIP 03237H101) tracked across SEC portfolio filings. 177 institutional managers reported $1.6B on Form 13F as of 2026-06-30; 19 registered fund positions totaling $50.9M via N-PORT as of 2026-05-31.

## Summary

- Issuer: AMYLYX PHARMACEUTICALS INC
- Class: COM
- CUSIP: 03237H101
- Asset category: EC
- 13F holders: 177
- 13F value: $1.6B
- 13F period: 2026-06-30
- N-PORT fund positions: 19
- N-PORT value: $50.9M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 177 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| FMR LLC | BOSTON, MA | $231.2M | 16,630,541 |
| BlackRock, Inc. | New York, NY | $122.7M | 8,828,836 |
| [PERCEPTIVE ADVISORS LLC](https://search.stillhousedata.com/firm/154703) | NEW YORK, NY | $115.2M | 8,284,882 |
| TCG Crossover Management, LLC | PALO ALTO, CA | $86.8M | 6,243,812 |
| [COMMODORE CAPITAL LP](https://search.stillhousedata.com/firm/304370) | NEW YORK, NY | $78.5M | 5,650,000 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $70.1M | 5,804,912 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $69.3M | 4,986,073 |
| [Saturn V Capital Management LP](https://search.stillhousedata.com/firm/316649) | AUSTIN, TX | $60.5M | 4,349,885 |
| [ADAGE CAPITAL PARTNERS GP, L.L.C.](https://search.stillhousedata.com/firm/160679) | Boston, MA | $49.5M | 3,560,764 |
| [First Light Asset Management, LLC](https://search.stillhousedata.com/firm/168899) | Edina, MN | $44.3M | 3,190,645 |
| Driehaus Capital Management LLC | Chicago, IL | $41.5M | 2,987,147 |
| GOLDMAN SACHS GROUP INC | NEW YORK, NY | $36.5M | 2,625,991 |
| STATE STREET CORP | BOSTON, MA | $32.8M | 2,363,161 |
| FRANKLIN RESOURCES INC | San Mateo, CA | $31.4M | 2,261,569 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://search.stillhousedata.com/firm/115504) | BOSTON, MA | $30.7M | 2,210,932 |

## Top fund holders (N-PORT)

_Showing 15 of 19 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $12.9M | 1.59% |
| [Fidelity Advisor Health Care Fund](https://search.stillhousedata.com/fund/S000005329) | Fidelity Advisor Series VII | $11.4M | 39.63% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $6.7M | 3.84% |
| [Fidelity Growth Company Fund](https://search.stillhousedata.com/fund/S000007119) | Fidelity Mt. Vernon Street Trust | $4.9M | 0.50% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $3.9M | 5.26% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $2.1M | 11.36% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $2.0M | 4.14% |
| [VIP Balanced Portfolio](https://search.stillhousedata.com/fund/S000007730) | Variable Insurance Products Fund III | $1.6M | 2.05% |
| [VANGUARD EXPLORER FUND](https://search.stillhousedata.com/fund/S000002578) | VANGUARD EXPLORER FUND | $1.0M | 0.47% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $789K | 0.13% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $678K | 0.22% |
| [Goldman Sachs ActiveBeta(R) U.S. Small Cap Equity ETF](https://search.stillhousedata.com/fund/S000048296) | Goldman Sachs ETF Trust | $626K | 6.35% |
| [Fidelity Nasdaq Composite Index ETF](https://search.stillhousedata.com/fund/S000006011) | Fidelity Commonwealth Trust | $572K | 0.52% |
| [PGIM Jennison Blend Fund](https://search.stillhousedata.com/fund/S000004514) | Prudential Jennison Blend Fund, Inc. | $507K | 4.33% |
| [Fidelity Balanced K6 Fund](https://search.stillhousedata.com/fund/S000065701) | Fidelity Puritan Trust | $446K | 1.84% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/03237H101.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

---

Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.