# EDGEWISE THERAPEUTICS INC COM

EDGEWISE THERAPEUTICS INC COM is a security (CUSIP 28036F105) tracked across SEC portfolio filings. 226 institutional managers reported $3.7B on Form 13F as of 2026-06-30; 21 registered fund positions totaling $110.5M via N-PORT as of 2026-05-31.

## Summary

- Issuer: EDGEWISE THERAPEUTICS INC
- Class: COM
- CUSIP: 28036F105
- Asset category: EC
- 13F holders: 226
- 13F value: $3.7B
- 13F period: 2026-06-30
- N-PORT fund positions: 21
- N-PORT value: $110.5M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 226 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [ORBIMED ADVISORS LLC](https://search.stillhousedata.com/firm/118608) | New York, NY | $488.8M | 15,518,492 |
| RA CAPITAL MANAGEMENT, L.P. | Boston, MA | $328.5M | 10,428,437 |
| [Paradigm Biocapital Advisors LP](https://search.stillhousedata.com/firm/312544) | NEW YORK, NY | $232.0M | 7,365,038 |
| [BAKER BROS. ADVISORS LP](https://search.stillhousedata.com/firm/158149) | NEW YORK, NY | $207.1M | 6,575,940 |
| BlackRock, Inc. | New York, NY | $203.9M | 6,472,991 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $186.3M | 5,915,556 |
| Novo Holdings A/S | HELLERUP, G7 | $168.5M | 5,350,000 |
| Driehaus Capital Management LLC | Chicago, IL | $141.1M | 4,477,942 |
| Siren, L.L.C. | New York, NY | $139.6M | 4,430,263 |
| [PERCEPTIVE ADVISORS LLC](https://search.stillhousedata.com/firm/154703) | NEW YORK, NY | $139.4M | 4,423,974 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $120.9M | 4,871,624 |
| [Cormorant Asset Management, LP](https://search.stillhousedata.com/firm/167820) | BOSTON, MA | $102.7M | 3,260,000 |
| [BRAIDWELL LP](https://search.stillhousedata.com/firm/316988) | STAMFORD, CT | $73.9M | 2,347,583 |
| MORGAN STANLEY | NEW YORK, NY | $70.7M | 2,246,028 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://search.stillhousedata.com/firm/115504) | BOSTON, MA | $56.4M | 1,789,819 |

## Top fund holders (N-PORT)

_Showing 15 of 21 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $26.0M | 3.19% |
| abrdn Healthcare Investors | abrdn Healthcare Investors | $14.9M | 131.04% |
| [AB DISCOVERY GROWTH FUND, INC.](https://search.stillhousedata.com/fund/S000010117) | AB DISCOVERY GROWTH FUND, INC. | $12.6M | 46.95% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $11.8M | 6.75% |
| abrdn Life Sciences Investors | abrdn Life Sciences Investors | $11.1M | 198.31% |
| [Janus Henderson Venture Fund](https://search.stillhousedata.com/fund/S000010488) | JANUS INVESTMENT FUND | $9.5M | 30.94% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $8.0M | 10.75% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $3.5M | 7.16% |
| BlackRock Health Sciences Term Trust | BlackRock Health Sciences Term Trust | $2.8M | 27.74% |
| [Optimum Small-Mid Cap Growth Fund](https://search.stillhousedata.com/fund/S000002424) | Optimum Fund Trust | $2.1M | 28.00% |
| [Small Cap Core Portfolio](https://search.stillhousedata.com/fund/S000051867) | Bernstein Fund Inc | $1.7M | 23.23% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $1.6M | 0.28% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $1.4M | 0.46% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $1.2M | 6.58% |
| [Fidelity Nasdaq Composite Index ETF](https://search.stillhousedata.com/fund/S000006011) | Fidelity Commonwealth Trust | $1.1M | 1.04% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/28036F105.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.