# KARYOPHARM THERAPEUTICS INC COM NEW

KARYOPHARM THERAPEUTICS INC COM NEW is a security (CUSIP 48576U205) tracked across SEC portfolio filings. 88 institutional managers reported $130.6M on Form 13F as of 2026-06-30; 6 registered fund positions totaling $6.3M via N-PORT as of 2026-03-31.

## Summary

- Issuer: KARYOPHARM THERAPEUTICS INC
- Class: COM NEW
- CUSIP: 48576U205
- Asset category: EC
- 13F holders: 88
- 13F value: $130.6M
- 13F period: 2026-06-30
- N-PORT fund positions: 6
- N-PORT value: $6.3M
- N-PORT report: 2026-03-31

## Top institutional holders (Form 13F)

_Showing 15 of 88 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [Ikarian Capital, LLC](https://search.stillhousedata.com/firm/1778253) | DALLAS, TX | $14.3M | 733,435 |
| [COMMODORE CAPITAL LP](https://search.stillhousedata.com/firm/304370) | NEW YORK, NY | $10.9M | 1,950,000 |
| RA CAPITAL MANAGEMENT, L.P. | Boston, MA | $10.7M | 1,917,354 |
| [ADAGE CAPITAL PARTNERS GP, L.L.C.](https://search.stillhousedata.com/firm/160679) | Boston, MA | $10.1M | 1,806,322 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | BALA CYNWYD, PA | $7.3M | 24,138 |
| [Caption Management, LLC](https://search.stillhousedata.com/firm/173841) | OKLAHOMA CITY, OK | $6.6M | — |
| GOLDMAN SACHS GROUP INC | NEW YORK, NY | $5.3M | 947,579 |
| [Catalio Capital Management, LP](https://search.stillhousedata.com/firm/310374) | NEW YORK, NY | $5.0M | 897,709 |
| [BOOTHBAY FUND MANAGEMENT, LLC](https://search.stillhousedata.com/firm/163706) | NEW YORK, NY | $4.2M | 213,810 |
| [Squadron Capital Management LLC](https://search.stillhousedata.com/firm/334296) | WESTMONT, IL | $4.2M | — |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $4.1M | 559,619 |
| JANE STREET GROUP, LLC | NEW YORK, NY | $3.3M | 105,901 |
| MILLENNIUM MANAGEMENT LLC | NEW YORK, NY | $2.8M | 420,571 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $2.8M | — |
| [Affinity Asset Advisors, LLC](https://search.stillhousedata.com/firm/312788) | New York, NY | $2.8M | 500,000 |

## Top fund holders (N-PORT)

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [T. Rowe Price Small-Cap Value Fund, Inc.](https://search.stillhousedata.com/fund/S000002121) | T. ROWE PRICE SMALL-CAP VALUE FUND, INC. | $4.9M | 5.29% |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $1.2M | 0.15% |
| [TIFF MULTI-ASSET FUND](https://search.stillhousedata.com/fund/S000006387) | TIFF Investment Program | $96K | 0.69% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $56K | 0.01% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $31K | 0.01% |
| [Blackstone Alternative Multi-Strategy Fund](https://search.stillhousedata.com/fund/S000045538) | Blackstone Alternative Investment Funds | $8K | 0.02% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/48576U205.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.