# LEXEO THERAPEUTICS INC COM

LEXEO THERAPEUTICS INC COM is a security (CUSIP 52886X107) tracked across SEC portfolio filings. 137 institutional managers reported $476.0M on Form 13F as of 2026-06-30; 9 registered fund positions totaling $10.3M via N-PORT as of 2026-05-31.

## Summary

- Issuer: LEXEO THERAPEUTICS INC
- Class: COM
- CUSIP: 52886X107
- Asset category: EC
- 13F holders: 137
- 13F value: $476.0M
- 13F period: 2026-06-30
- N-PORT fund positions: 9
- N-PORT value: $10.3M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 137 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $38.7M | 3,894,310 |
| [Paradigm Biocapital Advisors LP](https://search.stillhousedata.com/firm/312544) | NEW YORK, NY | $35.5M | 6,184,134 |
| BlackRock, Inc. | New York, NY | $29.3M | 5,110,871 |
| [Affinity Asset Advisors, LLC](https://search.stillhousedata.com/firm/312788) | New York, NY | $29.0M | 5,050,211 |
| RA CAPITAL MANAGEMENT, L.P. | Boston, MA | $28.7M | 5,000,000 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $28.5M | 4,976,429 |
| Vestal Point Capital, LP | NEW YORK, NY | $25.7M | 4,475,000 |
| [Frazier Life Sciences Management, L.P.](https://search.stillhousedata.com/firm/317522) | MENLO PARK, CA | $25.4M | 4,424,725 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $22.1M | 3,834,999 |
| [ORBIMED ADVISORS LLC](https://search.stillhousedata.com/firm/118608) | New York, NY | $20.7M | 3,602,450 |
| STATE STREET CORP | BOSTON, MA | $20.5M | 3,568,242 |
| [Woodline Partners LP](https://search.stillhousedata.com/firm/301480) | San Francisco, CA | $15.8M | 2,750,532 |
| GOLDMAN SACHS GROUP INC | NEW YORK, NY | $11.2M | 1,949,885 |
| [Avoro Capital Advisors LLC](https://search.stillhousedata.com/firm/154091) | New York, NY | $10.8M | 1,875,000 |
| [Point72 Asset Management, L.P.](https://search.stillhousedata.com/firm/283077) | Stamford, CT | $9.6M | 1,680,449 |

## Top fund holders (N-PORT)

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $3.9M | 0.47% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $1.7M | 0.99% |
| abrdn Life Sciences Investors | abrdn Life Sciences Investors | $1.4M | 25.17% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $1.2M | 1.54% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $1.0M | 5.52% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $613K | 1.27% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $229K | 0.04% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $205K | 0.07% |
| [DWS Small Cap Index VIP](https://search.stillhousedata.com/fund/S000006223) | DEUTSCHE DWS INVESTMENTS VIT FUNDS | $54K | 1.29% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/52886X107.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.