# Madrigal Pharmaceuticals, Inc. COM

Madrigal Pharmaceuticals, Inc. COM is a security (CUSIP 558868105) tracked across SEC portfolio filings. 411 institutional managers reported $12.6B on Form 13F as of 2026-06-30; 43 registered fund positions totaling $743.0M via N-PORT as of 2026-05-31.

## Summary

- Issuer: Madrigal Pharmaceuticals, Inc.
- Class: COM
- CUSIP: 558868105
- Asset category: EC
- 13F holders: 411
- 13F value: $12.6B
- 13F period: 2026-06-30
- N-PORT fund positions: 43
- N-PORT value: $743.0M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 411 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [BAKER BROS. ADVISORS LP](https://search.stillhousedata.com/firm/158149) | NEW YORK, NY | $1.1B | 2,141,701 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $1.1B | 1,808,894 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $1.1B | 2,018,647 |
| [RTW INVESTMENTS, LP](https://search.stillhousedata.com/firm/153232) | NEW YORK, NY | $1.0B | 1,993,687 |
| [Avoro Capital Advisors LLC](https://search.stillhousedata.com/firm/154091) | New York, NY | $951.8M | 1,818,181 |
| BlackRock, Inc. | New York, NY | $816.6M | 1,559,965 |
| [PAULSON & CO. INC.](https://search.stillhousedata.com/firm/127831) | NEW YORK, NY | $728.8M | 1,392,188 |
| WELLINGTON MANAGEMENT GROUP LLP | BOSTON, MA | $363.8M | 694,958 |
| STATE STREET CORP | BOSTON, MA | $319.1M | 609,525 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $315.4M | 453,843 |
| FMR LLC | BOSTON, MA | $267.9M | 511,728 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://search.stillhousedata.com/firm/115504) | BOSTON, MA | $238.7M | 455,870 |
| [WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC](https://search.stillhousedata.com/firm/173961) | CHICAGO, IL | $178.3M | 340,519 |
| [Polar Capital Holdings Plc](https://search.stillhousedata.com/firm/136133) | London, X0 | $151.4M | 289,310 |
| GOLDMAN SACHS GROUP INC | NEW YORK, NY | $145.2M | 277,371 |

## Top fund holders (N-PORT)

_Showing 15 of 43 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD HEALTH CARE FUND](https://search.stillhousedata.com/fund/S000002922) | VANGUARD SPECIALIZED FUNDS | $211.6M | 57.40% |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $108.8M | 13.35% |
| [VANGUARD EXPLORER FUND](https://search.stillhousedata.com/fund/S000002578) | VANGUARD EXPLORER FUND | $86.9M | 39.93% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $43.7M | 24.93% |
| [LORD ABBETT DEVELOPING GROWTH FUND INC](https://search.stillhousedata.com/fund/S000006834) | LORD ABBETT DEVELOPING GROWTH FUND, INC. | $42.5M | 191.28% |
| [T. Rowe Price Health Sciences Fund, Inc.](https://search.stillhousedata.com/fund/S000002088) | T. ROWE PRICE HEALTH SCIENCES FUND, INC. | $39.1M | 35.91% |
| [T. Rowe Price New Horizons Fund, Inc.](https://search.stillhousedata.com/fund/S000002106) | T. ROWE PRICE NEW HORIZONS FUND, INC. | $36.5M | 28.55% |
| [Janus Henderson Venture Fund](https://search.stillhousedata.com/fund/S000010488) | JANUS INVESTMENT FUND | $28.5M | 92.91% |
| ACAP Strategic Fund | ACAP Strategic Fund | $20.7M | 20.03% |
| [VALUE LINE LARGER COMPANIES FOCUSED FUND, INC.](https://search.stillhousedata.com/fund/S000007572) | Value Line Larger Companies Focused Fund, Inc. | $16.8M | 471.06% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $14.6M | 30.17% |
| [Columbia Acorn Fund](https://search.stillhousedata.com/fund/S000009184) | COLUMBIA ACORN TRUST | $13.8M | 61.67% |
| Advantage Advisers Xanthus Fund, L.L.C. | Advantage Advisers Xanthus Fund, L.L.C. | $11.8M | 39.70% |
| [AB DISCOVERY GROWTH FUND, INC.](https://search.stillhousedata.com/fund/S000010117) | AB DISCOVERY GROWTH FUND, INC. | $10.7M | 39.89% |
| [Fidelity Contrafund](https://search.stillhousedata.com/fund/S000006037) | Fidelity Contrafund | $10.3M | 0.65% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/558868105.md)
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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.