# MAZE THERAPEUTICS INC COM

MAZE THERAPEUTICS INC COM is a security (CUSIP 578784100) tracked across SEC portfolio filings. 166 institutional managers reported $1.6B on Form 13F as of 2026-06-30; 22 registered fund positions totaling $27.1M via N-PORT as of 2026-05-31.

## Summary

- Issuer: MAZE THERAPEUTICS INC
- Class: COM
- CUSIP: 578784100
- Asset category: EC
- 13F holders: 166
- 13F value: $1.6B
- 13F period: 2026-06-30
- N-PORT fund positions: 22
- N-PORT value: $27.1M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 166 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [Frazier Life Sciences Management, L.P.](https://search.stillhousedata.com/firm/317522) | MENLO PARK, CA | $136.3M | 4,567,274 |
| TRV GP IV, LLC | Boston, MA | $133.5M | 4,473,958 |
| [ARCH Venture Management, LLC](https://search.stillhousedata.com/firm/158196) | CHICAGO, IL | $123.0M | 4,120,053 |
| Deep Track Capital, LP | GREENWICH, CT | $103.8M | 3,477,562 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $85.3M | 2,858,876 |
| [Paradigm Biocapital Advisors LP](https://search.stillhousedata.com/firm/312544) | NEW YORK, NY | $81.9M | 2,744,399 |
| BlackRock, Inc. | New York, NY | $76.7M | 2,570,425 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $70.3M | 1,697,015 |
| [a16z Capital Management, L.L.C.](https://search.stillhousedata.com/firm/160489) | MENLO PARK, CA | $50.8M | 1,702,225 |
| [VR Adviser, LLC](https://search.stillhousedata.com/firm/169288) | NEW YORK, NY | $47.8M | 1,602,034 |
| Alphabet Inc. | Mountain View, CA | $41.4M | 1,388,583 |
| [Logos Global Management LP](https://search.stillhousedata.com/firm/305162) | San Francisco, CA | $36.9M | 1,235,000 |
| [ADAGE CAPITAL PARTNERS GP, L.L.C.](https://search.stillhousedata.com/firm/160679) | Boston, MA | $35.2M | 1,178,000 |
| [General Catalyst Group Management, LLC](https://search.stillhousedata.com/firm/162548) | Cambridge, MA | $30.9M | 1,035,910 |
| TRV GP V, LLC | Boston, MA | $28.4M | 950,800 |

## Top fund holders (N-PORT)

_Showing 15 of 22 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $7.0M | 0.86% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $3.6M | 2.05% |
| abrdn Healthcare Investors | abrdn Healthcare Investors | $3.3M | 29.34% |
| [Fidelity Growth Company Fund](https://search.stillhousedata.com/fund/S000007119) | Fidelity Mt. Vernon Street Trust | $2.5M | 0.26% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $2.1M | 11.48% |
| abrdn World Healthcare Fund | abrdn World Healthcare Fund | $1.8M | 37.15% |
| abrdn Life Sciences Investors | abrdn Life Sciences Investors | $1.6M | 29.08% |
| BlackRock Health Sciences Term Trust | BlackRock Health Sciences Term Trust | $1.3M | 13.19% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $1.3M | 2.66% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $620K | 0.11% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $526K | 0.17% |
| BlackRock Health Sciences Trust | BlackRock Health Sciences Trust | $477K | 8.95% |
| [Fidelity Nasdaq Composite Index ETF](https://search.stillhousedata.com/fund/S000006011) | Fidelity Commonwealth Trust | $376K | 0.34% |
| [T. Rowe Price Spectrum Moderate Growth Allocation Fund](https://search.stillhousedata.com/fund/S000002138) | T. ROWE PRICE SPECTRUM FUNDS II, INC. | $268K | 0.62% |
| [Russell Investments U.S. Small Cap Equity ETF](https://search.stillhousedata.com/fund/S000089990) | Russell Investments Exchange Traded Funds | $175K | 35.37% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/578784100.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.