# PROTAGONIST THERAPEUTICS INC COM

PROTAGONIST THERAPEUTICS INC COM is a security (CUSIP 74366E102) tracked across SEC portfolio filings. 346 institutional managers reported $8.5B on Form 13F as of 2026-06-30; 35 registered fund positions totaling $541.7M via N-PORT as of 2026-05-31.

## Summary

- Issuer: PROTAGONIST THERAPEUTICS INC
- Class: COM
- CUSIP: 74366E102
- Asset category: EC
- 13F holders: 346
- 13F value: $8.5B
- 13F period: 2026-06-30
- N-PORT fund positions: 35
- N-PORT value: $541.7M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 346 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| BlackRock, Inc. | New York, NY | $1.0B | 9,779,369 |
| [FARALLON CAPITAL MANAGEMENT LLC](https://search.stillhousedata.com/firm/107322) | SAN FRANCISCO, CA | $669.2M | 6,348,906 |
| UBS Group AG | Zurich, V8 | $545.7M | 5,177,796 |
| [RTW INVESTMENTS, LP](https://search.stillhousedata.com/firm/153232) | NEW YORK, NY | $533.2M | 5,059,053 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $472.8M | 5,413,690 |
| WELLINGTON MANAGEMENT GROUP LLP | BOSTON, MA | $379.4M | 3,599,644 |
| [VANGUARD PORTFOLIO MANAGEMENT LLC](https://search.stillhousedata.com/firm/338003) | MALVERN, PA | $366.9M | 3,481,211 |
| STATE STREET CORP | BOSTON, MA | $328.5M | 3,116,749 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $304.9M | 2,891,527 |
| JOHNSON & JOHNSON | NEW BRUNSWICK, NJ | $300.2M | 2,449,183 |
| [VANGUARD CAPITAL MANAGEMENT LLC](https://search.stillhousedata.com/firm/338002) | MALVERN, PA | $295.7M | 2,805,896 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://search.stillhousedata.com/firm/115504) | BOSTON, MA | $176.0M | 1,669,371 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $169.1M | 1,551,900 |
| [Woodline Partners LP](https://search.stillhousedata.com/firm/301480) | San Francisco, CA | $149.1M | 1,414,173 |
| [JENNISON ASSOCIATES LLC](https://search.stillhousedata.com/firm/107959) | NEW YORK, NY | $141.2M | 1,151,681 |

## Top fund holders (N-PORT)

_Showing 15 of 35 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD HEALTH CARE FUND](https://search.stillhousedata.com/fund/S000002922) | VANGUARD SPECIALIZED FUNDS | $136.6M | 37.06% |
| [T. Rowe Price Health Sciences Fund, Inc.](https://search.stillhousedata.com/fund/S000002088) | T. ROWE PRICE HEALTH SCIENCES FUND, INC. | $120.4M | 110.50% |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $69.2M | 8.49% |
| [Janus Henderson Venture Fund](https://search.stillhousedata.com/fund/S000010488) | JANUS INVESTMENT FUND | $34.3M | 111.91% |
| [PGIM Jennison Small Company Fund](https://search.stillhousedata.com/fund/S000004629) | Prudential Jennison Small Co Fund, Inc. | $33.1M | 103.82% |
| [VANGUARD EXPLORER FUND](https://search.stillhousedata.com/fund/S000002578) | VANGUARD EXPLORER FUND | $32.9M | 15.12% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $29.8M | 16.98% |
| [LORD ABBETT DEVELOPING GROWTH FUND INC](https://search.stillhousedata.com/fund/S000006834) | LORD ABBETT DEVELOPING GROWTH FUND, INC. | $13.7M | 61.74% |
| [PGIM Jennison Health Sciences Fund](https://search.stillhousedata.com/fund/S000004380) | Prudential Sector Funds, Inc. | $13.5M | 96.99% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $10.0M | 20.67% |
| [T. Rowe Price Health Sciences Portfolio](https://search.stillhousedata.com/fund/S000002083) | T. ROWE PRICE EQUITY SERIES, INC. | $7.3M | 110.81% |
| BlackRock Health Sciences Term Trust | BlackRock Health Sciences Term Trust | $7.3M | 71.70% |
| [HARTFORD SMALL COMPANY HLS FUND](https://search.stillhousedata.com/fund/S000003220) | HARTFORD SERIES FUND INC | $4.5M | 115.67% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $3.9M | 5.15% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $3.8M | 0.64% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/74366E102.md)
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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.