# SILENCE THERAPEUTICS PLC ADRS

SILENCE THERAPEUTICS PLC ADRS is a security (CUSIP 82686Q101) tracked across SEC portfolio filings. 61 institutional managers reported $104.0M on Form 13F as of 2026-06-30; 3 registered fund positions totaling $48K via N-PORT as of 2026-04-30.

## Summary

- Issuer: SILENCE THERAPEUTICS PLC
- Class: ADRS
- CUSIP: 82686Q101
- Asset category: EC
- 13F holders: 61
- 13F value: $104.0M
- 13F period: 2026-06-30
- N-PORT fund positions: 3
- N-PORT value: $48K
- N-PORT report: 2026-04-30

## Top institutional holders (Form 13F)

_Showing 15 of 61 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| TCG Crossover Management, LLC | PALO ALTO, CA | $16.0M | 3,033,560 |
| Siren, L.L.C. | New York, NY | $15.3M | 2,911,438 |
| [Redmile Group, LLC](https://search.stillhousedata.com/firm/143606) | San Francisco, CA | $11.4M | 2,164,777 |
| Nantahala Capital Management, LLC | New Canaan, CT | $11.3M | 2,146,731 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $6.6M | 1,234,807 |
| MILLENNIUM MANAGEMENT LLC | NEW YORK, NY | $5.7M | 1,074,191 |
| [GREAT POINT PARTNERS LLC](https://search.stillhousedata.com/firm/158423) | Greenwich, CT | $5.4M | 1,020,489 |
| [Nextech Invest, Ltd.](https://search.stillhousedata.com/firm/322629) | Zurich, V8 | $5.0M | 952,400 |
| [TFG Asset Management GP Ltd](https://search.stillhousedata.com/firm/156040) | Grand Cayman, E9 | $3.3M | 630,161 |
| [5AM Venture Management, LLC](https://search.stillhousedata.com/firm/160395) | San Francisco, CA | $2.5M | 476,200 |
| BlackRock, Inc. | New York, NY | $2.4M | 219,917 |
| [Ikarian Capital, LLC](https://search.stillhousedata.com/firm/1778253) | DALLAS, TX | $1.7M | 865,784 |
| [Jones Hill Capital LP](https://search.stillhousedata.com/firm/339686) | NEW YORK, NY | $1.6M | 301,604 |
| UBS Group AG | Zurich, V8 | $1.3M | 246,937 |
| [Quadrature Capital Ltd](https://search.stillhousedata.com/firm/281598) | LONDON, X0 | $1.3M | 118,129 |

## Top fund holders (N-PORT)

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [Steward Values Enhanced International Fund](https://search.stillhousedata.com/fund/S000010863) | Steward Funds Inc | $42K | 1.40% |
| [Blackstone Alternative Multi-Strategy Fund](https://search.stillhousedata.com/fund/S000045538) | Blackstone Alternative Investment Funds | $5K | 0.01% |
| [College Retirement Equities Fund - Total Global Stock Account](https://search.stillhousedata.com/fund/S000005080) | College Retirement Equities Fund | $126 | 0.00% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/82686Q101.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.