# TYRA BIOSCIENCES INC COMMON STOCK

TYRA BIOSCIENCES INC COMMON STOCK is a security (CUSIP 90240B106) tracked across SEC portfolio filings. 166 institutional managers reported $2.4B on Form 13F as of 2026-06-30; 20 registered fund positions totaling $61.9M via N-PORT as of 2026-05-31.

## Summary

- Issuer: TYRA BIOSCIENCES INC
- Class: COMMON STOCK
- CUSIP: 90240B106
- Asset category: EC
- 13F holders: 166
- 13F value: $2.4B
- 13F period: 2026-06-30
- N-PORT fund positions: 20
- N-PORT value: $61.9M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 166 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| RA CAPITAL MANAGEMENT, L.P. | Boston, MA | $467.2M | 12,198,625 |
| FMR LLC | BOSTON, MA | $296.7M | 7,747,648 |
| [Nextech Invest, Ltd.](https://search.stillhousedata.com/firm/322629) | Zurich, V8 | $155.3M | 4,055,861 |
| JANUS HENDERSON GROUP PLC | LONDON, X0 | $148.9M | 3,890,589 |
| [FARALLON CAPITAL MANAGEMENT LLC](https://search.stillhousedata.com/firm/107322) | SAN FRANCISCO, CA | $137.1M | 3,580,818 |
| TCG Crossover Management, LLC | PALO ALTO, CA | $124.4M | 3,248,980 |
| [Alta Partners Management Company, L.P.](https://search.stillhousedata.com/firm/288423) | JACKSON, WY | $122.1M | 3,823,425 |
| [COMMODORE CAPITAL LP](https://search.stillhousedata.com/firm/304370) | NEW YORK, NY | $94.8M | 2,475,000 |
| BlackRock, Inc. | New York, NY | $84.9M | 2,217,929 |
| [Paradigm Biocapital Advisors LP](https://search.stillhousedata.com/firm/312544) | NEW YORK, NY | $78.7M | 2,054,991 |
| BVF INC/IL | San Francisco, CA | $75.7M | 1,976,196 |
| [Caligan Partners LP](https://search.stillhousedata.com/firm/289887) | New York, NY | $48.9M | 1,276,968 |
| STATE STREET CORP | BOSTON, MA | $46.6M | 1,216,078 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $41.3M | 1,572,785 |
| [5AM Venture Management, LLC](https://search.stillhousedata.com/firm/160395) | San Francisco, CA | $39.4M | 1,029,298 |

## Top fund holders (N-PORT)

_Showing 15 of 20 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [T. Rowe Price Health Sciences Fund, Inc.](https://search.stillhousedata.com/fund/S000002088) | T. ROWE PRICE HEALTH SCIENCES FUND, INC. | $11.8M | 10.80% |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $10.1M | 1.23% |
| [T. Rowe Price New Horizons Fund, Inc.](https://search.stillhousedata.com/fund/S000002106) | T. ROWE PRICE NEW HORIZONS FUND, INC. | $8.5M | 6.64% |
| [Janus Henderson Venture Fund](https://search.stillhousedata.com/fund/S000010488) | JANUS INVESTMENT FUND | $7.8M | 25.53% |
| [PGIM Jennison Health Sciences Fund](https://search.stillhousedata.com/fund/S000004380) | Prudential Sector Funds, Inc. | $6.1M | 44.00% |
| [Fidelity Advisor Health Care Fund](https://search.stillhousedata.com/fund/S000005329) | Fidelity Advisor Series VII | $4.9M | 16.85% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $4.4M | 2.54% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $2.7M | 14.84% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $1.6M | 3.31% |
| [T. Rowe Price Health Sciences Portfolio](https://search.stillhousedata.com/fund/S000002083) | T. ROWE PRICE EQUITY SERIES, INC. | $720K | 10.87% |
| [Fidelity Nasdaq Composite Index ETF](https://search.stillhousedata.com/fund/S000006011) | Fidelity Commonwealth Trust | $603K | 0.55% |
| [Franklin Alternative Strategies Fund](https://search.stillhousedata.com/fund/S000042023) | Franklin Alternative Strategies Funds | $586K | 9.94% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $563K | 0.10% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $480K | 0.16% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $475K | 0.64% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/90240B106.md)
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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.