# XERIS BIOPHARMA HOLDINGS INC COM

XERIS BIOPHARMA HOLDINGS INC COM is a security (CUSIP 98422E103) tracked across SEC portfolio filings. 241 institutional managers reported $704.9M on Form 13F as of 2026-06-30; 20 registered fund positions totaling $31.1M via N-PORT as of 2026-05-31.

## Summary

- Issuer: XERIS BIOPHARMA HOLDINGS INC
- Class: COM
- CUSIP: 98422E103
- Asset category: EC
- 13F holders: 241
- 13F value: $704.9M
- 13F period: 2026-06-30
- N-PORT fund positions: 20
- N-PORT value: $31.1M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 241 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $87.8M | 11,186,677 |
| BlackRock, Inc. | New York, NY | $75.1M | 12,945,785 |
| D. E. Shaw & Co., Inc. | New York, NY | $45.2M | 7,788,811 |
| [VANGUARD CAPITAL MANAGEMENT LLC](https://search.stillhousedata.com/firm/338002) | MALVERN, PA | $40.5M | 6,980,882 |
| STATE STREET CORP | BOSTON, MA | $27.0M | 4,658,174 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://search.stillhousedata.com/firm/115504) | BOSTON, MA | $24.9M | 4,290,629 |
| [Qube Research & Technologies Ltd](https://search.stillhousedata.com/firm/304552) | LONDON, X0 | $23.9M | 4,114,425 |
| Rosalind Advisors, Inc. | TORONTO, A6 | $18.7M | 3,231,700 |
| Nuveen, LLC | CHARLOTTE, NC | $16.9M | 2,916,598 |
| [VANGUARD PORTFOLIO MANAGEMENT LLC](https://search.stillhousedata.com/firm/338003) | MALVERN, PA | $15.5M | 2,665,608 |
| MORGAN STANLEY | NEW YORK, NY | $14.9M | 2,572,654 |
| MILLENNIUM MANAGEMENT LLC | NEW YORK, NY | $13.1M | 2,265,974 |
| WELLINGTON MANAGEMENT GROUP LLP | BOSTON, MA | $12.6M | 2,171,354 |
| [TWO SIGMA INVESTMENTS, LP](https://search.stillhousedata.com/firm/137137) | New York, NY | $11.2M | 1,924,202 |
| [ARMISTICE CAPITAL, LLC](https://search.stillhousedata.com/firm/168978) | NEW YORK, NY | $11.1M | 1,909,838 |

## Top fund holders (N-PORT)

_Showing 15 of 20 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD EXTENDED MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002841) | VANGUARD INDEX FUNDS | $10.8M | 1.32% |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $5.0M | 2.87% |
| [VANGUARD EXPLORER FUND](https://search.stillhousedata.com/fund/S000002578) | VANGUARD EXPLORER FUND | $3.0M | 1.38% |
| [TIFF MULTI-ASSET FUND](https://search.stillhousedata.com/fund/S000006387) | TIFF Investment Program | $2.4M | 17.17% |
| [VOYA SMALL COMPANY PORTFOLIO](https://search.stillhousedata.com/fund/S000008709) | Voya VARIABLE PORTFOLIOS INC | $2.0M | 111.75% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $1.5M | 3.03% |
| [VANGUARD STRATEGIC EQUITY FUND](https://search.stillhousedata.com/fund/S000002593) | VANGUARD HORIZON FUNDS | $1.3M | 1.26% |
| [1290 Essex Small Cap Growth Fund](https://search.stillhousedata.com/fund/S000076802) | 1290 Funds | $1.1M | 95.32% |
| [Voya MI Dynamic Small Cap Fund](https://search.stillhousedata.com/fund/S000066937) | Voya Equity Trust | $863K | 46.33% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $690K | 3.76% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $531K | 0.09% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $475K | 0.16% |
| [Russell Investments U.S. Small Cap Equity ETF](https://search.stillhousedata.com/fund/S000089990) | Russell Investments Exchange Traded Funds | $388K | 78.68% |
| [Goldman Sachs ActiveBeta(R) U.S. Small Cap Equity ETF](https://search.stillhousedata.com/fund/S000048296) | Goldman Sachs ETF Trust | $378K | 3.83% |
| [VANGUARD GROWTH AND INCOME FUND](https://search.stillhousedata.com/fund/S000002913) | VANGUARD QUANTITATIVE FUNDS | $356K | 0.22% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/98422e103.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.