# ZYMEWORKS INC COM

ZYMEWORKS INC COM is a security (CUSIP 98985Y108) tracked across SEC portfolio filings. 211 institutional managers reported $1.8B on Form 13F as of 2026-06-30; 19 registered fund positions totaling $22.0M via N-PORT as of 2026-05-31.

## Summary

- Issuer: ZYMEWORKS INC
- Class: COM
- CUSIP: 98985Y108
- Asset category: EC
- 13F holders: 211
- 13F value: $1.8B
- 13F period: 2026-06-30
- N-PORT fund positions: 19
- N-PORT value: $22.0M
- N-PORT report: 2026-05-31

## Top institutional holders (Form 13F)

_Showing 15 of 211 managers by value._

| Manager | Location | Value | Shares |
| --- | --- | --- | --- |
| [EcoR1 Capital, LLC](https://search.stillhousedata.com/firm/167121) | San Francisco, CA | $575.2M | 22,970,388 |
| Rubric Capital Management LP | New York, NY | $175.3M | 7,000,000 |
| BlackRock, Inc. | New York, NY | $114.0M | 4,553,888 |
| BVF INC/IL | San Francisco, CA | $93.5M | 3,734,142 |
| [PERCEPTIVE ADVISORS LLC](https://search.stillhousedata.com/firm/154703) | NEW YORK, NY | $87.9M | 3,510,078 |
| MORGAN STANLEY | NEW YORK, NY | $62.1M | 2,480,568 |
| [VANGUARD GROUP INC](https://search.stillhousedata.com/firm/105958) | Valley Forge, PA | $61.3M | 2,328,727 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Paris, I0 | $47.8M | 1,908,039 |
| Assenagon Asset Management S.A. | SENNINGERBERG, N4 | $32.7M | 1,252,027 |
| [CITADEL ADVISORS LLC](https://search.stillhousedata.com/firm/148826) | MIAMI, FL | $31.3M | 1,150,018 |
| DIMENSIONAL FUND ADVISORS LP | AUSTIN, TX | $28.5M | 1,139,135 |
| [Nextech Invest, Ltd.](https://search.stillhousedata.com/firm/322629) | Zurich, V8 | $27.9M | 1,113,946 |
| STATE STREET CORP | BOSTON, MA | $25.3M | 1,011,777 |
| DEUTSCHE BANK AG\\ | Frankfurt Am Main, 2M | $23.1M | 921,250 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | BOSTON, MA | $18.6M | 743,898 |

## Top fund holders (N-PORT)

_Showing 15 of 19 fund positions by value._

| Fund | Registrant | Value | % of fund |
| --- | --- | --- | --- |
| [VANGUARD RUSSELL 2000 INDEX FUND](https://search.stillhousedata.com/fund/S000030003) | VANGUARD SCOTTSDALE FUNDS | $6.4M | 3.67% |
| [U.S. MICRO CAP PORTFOLIO](https://search.stillhousedata.com/fund/S000000948) | DFA INVESTMENT DIMENSIONS GROUP INC | $4.7M | 6.33% |
| ROYCE SMALL-CAP TRUST, INC. | ROYCE SMALL-CAP TRUST, INC. | $3.7M | 16.47% |
| [Master Small Cap Index Series](https://search.stillhousedata.com/fund/S000002716) | Quantitative Master Series LLC | $2.0M | 4.14% |
| [VANGUARD U.S. MOMENTUM FACTOR ETF](https://search.stillhousedata.com/fund/S000061302) | VANGUARD WELLINGTON FUND | $1.9M | 10.19% |
| [VANGUARD BALANCED INDEX FUND](https://search.stillhousedata.com/fund/S000002560) | VANGUARD VALLEY FORGE FUNDS | $739K | 0.13% |
| [BlackRock Advantage SMID Cap Fund, Inc.](https://search.stillhousedata.com/fund/S000002323) | BlackRock Advantage SMID Cap Fund, Inc. | $719K | 9.51% |
| [Fidelity Nasdaq Composite Index ETF](https://search.stillhousedata.com/fund/S000006011) | Fidelity Commonwealth Trust | $674K | 0.62% |
| [VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND](https://search.stillhousedata.com/fund/S000002855) | VANGUARD INSTITUTIONAL INDEX FUNDS | $620K | 0.20% |
| [Goldman Sachs ActiveBeta(R) U.S. Small Cap Equity ETF](https://search.stillhousedata.com/fund/S000048296) | Goldman Sachs ETF Trust | $274K | 2.77% |
| [DWS Small Cap Index VIP](https://search.stillhousedata.com/fund/S000006223) | DEUTSCHE DWS INVESTMENTS VIT FUNDS | $175K | 4.16% |
| Gabelli Healthcare & WellnessRx Trust | Gabelli Healthcare & WellnessRx Trust | $125K | 8.46% |
| [TIAA Separate Account VA-1 - Stock Index Account](https://search.stillhousedata.com/fund/S000005098) | TIAA Separate Account VA-1 | $35K | 0.28% |
| [Putnam Multi-Asset Income Fund](https://search.stillhousedata.com/fund/S000067964) | Putnam Asset Allocation Funds | $16K | 0.17% |
| [Humankind U.S. Stock ETF](https://search.stillhousedata.com/fund/S000069946) | Humankind Benefit Corp | $11K | 0.67% |

## More

- [This page as markdown (for LLM agents)](https://search.stillhousedata.com/security/98985Y108.md)
- [Search all SEC filings, advisers and people on Adviser Search](https://search.stillhousedata.com/)

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Source: public SEC filing data via Adviser Search (https://search.stillhousedata.com).
Agents: this data is also queryable via MCP tools and read-only SQL — see https://search.stillhousedata.com/llms.txt.