SPERO THERAPEUTICS INC COM is a security (CUSIP 84833T103) tracked across SEC portfolio filings. 53 institutional managers reported $48.1M on Form 13F as of 2026-06-30; 6 registered fund positions totaling $1.4M via N-PORT as of 2026-05-31.
Showing 15 of 53 managers by value.
| Manager | Location | Value | Shares |
|---|---|---|---|
| GSK plc | London, X0 | $21.5M | 9,190,606 |
| Pfizer Inc | New York, NY | $5.5M | 2,362,348 |
| VANGUARD GROUP INC | Valley Forge, PA | $4.9M | 2,083,462 |
| RENAISSANCE TECHNOLOGIES LLC | NEW YORK, NY | $2.8M | 1,189,235 |
| Alphabet Inc. | Mountain View, CA | $2.1M | 889,979 |
| TWO SIGMA INVESTMENTS, LP | New York, NY | $2.1M | 885,631 |
| GEODE CAPITAL MANAGEMENT, LLC | BOSTON, MA | $1.2M | 519,922 |
| BlackRock, Inc. | New York, NY | $1.0M | 433,202 |
| CITADEL ADVISORS LLC | MIAMI, FL | $996K | 376,458 |
| Anson Funds Management LP | DALLAS, TX | $987K | 421,956 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | BALA CYNWYD, PA | $893K | 333,115 |
| STATE STREET CORP | BOSTON, MA | $503K | 214,751 |
| Ionic Capital Management LLC | NEW YORK, NY | $458K | 195,939 |
| Squarepoint Ops LLC | New York, NY | $455K | 194,301 |
| JANE STREET GROUP, LLC | NEW YORK, NY | $427K | 106,345 |
| Fund | Registrant | Value | % of fund |
|---|---|---|---|
| VANGUARD EXTENDED MARKET INDEX FUND | VANGUARD INDEX FUNDS | $1.2M | 0.15% |
| Invesco NASDAQ Future Gen 200 ETF | Invesco Exchange-Traded Fund Trust II | $101K | 53.28% |
| VANGUARD BALANCED INDEX FUND | VANGUARD VALLEY FORGE FUNDS | $57K | 0.01% |
| VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND | VANGUARD INSTITUTIONAL INDEX FUNDS | $53K | 0.02% |
| Blackstone Alternative Multi-Strategy Fund | Blackstone Alternative Investment Funds | $14K | 0.04% |
| Guggenheim Active Allocation Fund | Guggenheim Active Allocation Fund | $408 | 0.01% |