State Street(R) SPDR(R) S&P(R) Biotech ETF

State Street(R) SPDR(R) S&P(R) Biotech ETF is a ETF series of SPDR SERIES TRUST (series S000010018). Net assets $7.4B as of 2026-03-31. Index fund.

Profile

Advisers

Top holdings (158 reported)

Showing 15 of 158 holdings by value.

HoldingTickerValue% of fund
State Street Global Advisors$595.5M800.95%
Apellis Pharmaceuticals Inc$136.4M183.47%
Alkermes PLC$107.9M145.10%
Madrigal Pharmaceuticals Inc$102.8M138.29%
TG Therapeutics Inc$100.3M134.96%
Insmed Inc$99.4M133.69%
Scholar Rock Holding Corp$96.5M129.73%
Apogee Therapeutics Inc$95.5M128.43%
Protagonist Therapeutics Inc$92.5M124.49%
Summit Therapeutics Inc$92.3M124.11%
United Therapeutics Corp$92.2M124.05%
Praxis Precision Medicines Inc$91.9M123.62%
Arrowhead Pharmaceuticals Inc$91.4M122.98%
Cogent Biosciences Inc$90.4M121.57%
Bridgebio Pharma Inc$88.1M118.55%

Net asset history

Report dateNet assets
2026-03-31$7.4B
2025-12-31$7.8B
2025-09-30$5.7B
2025-06-30$4.8B
2025-03-31$5.1B
2024-12-31$6.4B
2024-09-30$7.7B
2024-06-30$7.1B

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